Self-drilling screws are versatile fasteners designed to be used with a wide range of materials. They have a drill bit-like tip that allows them to create their own pilot holes as they are driven into the material. Here are some of the common materials for which self-drilling screws are suitable:

Metal: Self-drilling screws are frequently used with various metals, including steel, aluminum, brass, copper, and stainless steel. They are commonly employed in metal roofing, steel framing, and sheet metal applications.

Wood: These screws can be used with various wood types, including hardwoods, softwoods, and engineered wood products. They are commonly used in carpentry, woodworking, and deck construction.

Plastic: Self-drilling screws work well with different types of plastic materials, such as PVC, acrylic, and polycarbonate. They are used in applications like plastic sheet installation and assembly.

Masonry: Some self-drilling screws are designed for masonry and concrete applications. These screws have special tips for drilling into masonry materials.

Drywall: Self-drilling screws are commonly used in drywall installation. They help secure drywall sheets to wooden or metal studs.

Composite Materials: These screws can be used with composite materials, such as fiberglass and carbon fiber composites, often found in boat building, aerospace, and automotive industries.

Fiberglass: Self-drilling screws are suitable for attaching fiberglass panels and components in applications like boat building and construction.

Sheet Metal: They are ideal for joining thin sheet metal components, making them a staple in automotive and HVAC industries.

Roofing: Self-drilling screws are widely used in attaching roofing materials, including metal, asphalt shingles, and corrugated roofing panels.

Fencing: They are used for attaching fence panels made of various materials, including wood, metal, and PVC.

Insulation: Self-drilling screws can be used to secure insulation materials to framing in construction and HVAC applications.

Electrical Boxes: They are employed in securing electrical boxes to wall studs or other mounting surfaces in electrical installations.

Furniture Assembly: Self-drilling screws are commonly used in DIY furniture assembly kits, where they secure various components made of wood or metal.

It's important to choose the appropriate self-drilling screw type and size for the specific material and application to ensure a secure and reliable connection. Additionally, self-drilling screws may come with different coatings or finishes to enhance corrosion resistance or improve aesthetics, depending on the material and environment in which they will be used.